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Principal Investigator
Richard D. Urman, MD, MBA, FASA Associate Professor of AnesthesiaHarvard Medical School

Richard D. Urman, MD, MBA, FASA


The mission of the Center for Perioperative Research is to facilitate research projects designed to test strategies that promote high quality perioperative care. Our research can be grouped into the following categories:

  1. Clinical trials of new drugs and devices
  2. Using informatics tools and large clinical databases to study perioperative/periprocedural patient outcomes and management strategies
  3. Patient safety research
  4. Opioid-related complications and non-opioid management strategies

We created a unique and innovative collaborative model of clinical and translational research by engaging anesthesiologists, surgeons, and members of medicine and other departments designed to improve quality of perioperative care, realize cost savings, and foster education. Our funded research activities include clinical trials of new pharmaceutical agents, patient monitoring techniques, and novel devices. Other recent projects have focused on understanding clinical risk factors for post-discharge surgical readmissions and reoperations using hospital and national outcomes data. Some of the projects involve investigation of the efficacy of informatics-based clinical decision tools, efficacy of perioperative (OR and Non-OR) efficiency interventions, and enhanced recovery after surgery (ERAS) pathways. We have performed analysis of quality metrics and patient outcomes using national databases to study patient mortality, care patterns, complication rates, and healthcare utilization. Recent work has focused on using large clinical databases such as NSQIP, NIS, Medicare/Medicaid, NACOR and closed claims, to examine the impact of anesthetic and surgical factors on patient outcomes. Several recent projects examined the impact of regional anesthesia on short-term patient outcomes. Our patient safety-related research has been focused on the use of emergency manuals in the OR, including a recent multi-institutional study funded by the Anesthesia Patient Safety Foundation (APSF). There is also an ongoing study on the preoperative goals of care discussions and shared decision making funded by the Foundation for Anesthesia Education and Research (FAER). The Center is currently working on a collaborative project to identify risk factors for opioid-related complications in hospitalized surgical patients, discharge order sets to improve care transitions, and identify predictors of persistent opioid use and opioid-related complications.

Edward E. Whang, MD

Edward E. Whang, MD, FACS

Other Members
Ethan Brovman

Ethan Y. Brovman, MD

Jason Gold tall

Jason S. Gold, MD

Sergey Karamnov, MD
Instructor in Anesthesia | Harvard Medical School

Sergey Karamnov, MD

Alexander Stone

Alexander B. Stone, MD

Richard Urman

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